How can we exercise precise control over matter?
What would chemistry look like if it was re-formulated using today’s tools and techniques?
New reaction media
Chemical reactions happen in all sorts of places in nature. Why constrain ourselves to the round bottom flask?
Relevant publications
- In situ synthesis within micron-sized hydrogel reactors created via programmable aerosol chemistry
Zhang, L.; Mehr, S. H. M., RSC Digital Discovery, 2024
High bandwidth analytical methods
How much raw information can we extract from a single experiment?
Relevant publications
- Detection of Micron-Sized Chemical Droplets Using a Commodity Digital Camera Setup
Jiang, H.; Mehr, S. H. M. ChemRxiv, 2023
Probabilistic methods
Can we apply chemical theories and expertise to interpret vast amounts of experimental data, even if the evidence is noisy and uncertain?
Languages and automation
Can chemistry experiments be defined by computer code?
Publications
2025
- Digital discovery and the new experimental frontier
Mehr, S. H. M. (preprint)
2024
- In situ synthesis within micron-sized hydrogel reactors created via programmable aerosol chemistry
Zhang, L.; Mehr, S. H. M., RSC Digital Discovery, 2024 - Investigating and Quantifying Molecular Complexity Using Assembly Theory and Spectroscopy
Jirasek, M; Sharma, A; Bame, J. R.; Mehr, S. H. M.; et al ACS Cent. Sci., 2024, 10, 1054 - Evidence of Selection in Mineral Mediated Polymerization Reactions Executed in a Robotic Chemputer System
Asche, S.; Pow, R.; Mehr, H. M.; Cooper, G.; Sharma, A.; Cronin, L., ChemSystemsChem, 2024, 6, e202400006 - An integrated self-optimizing programmable chemical synthesis and reaction engine
Leonov, A. I.; Hammer, A. J. S.; Lach, S.; Mehr, S. H. M.; et al Nat. Comm., 2024, 15, 1240
Collaborative outputs
- Constructing the Molecular Tree of Life using Assembly Theory and Mass Spectrometry
Kahana, A.; MacLeod, A.; Mehr, S. H. M.; Sharma, A.; Carrick, E.; Jirasek, M.; et al arXiv., 2024 - Assembly Theory and position-specific isotope analysis for distinguishing biotic and abiotic processes
Weiss, G.; Sacks, J.; Mehr, S. H. M.; Rutter, L.; Cronin, L.; Graham, H. Astrobiology Science Conference, 2024
2023
- Detection of Micron-Sized Chemical Droplets Using a Commodity Digital Camera Setup
Jiang, H.; Mehr, S. H. M. ChemRxiv, 2023 - Digitizing chemical discovery with a Bayesian explorer for interpreting reactivity data
Mehr, S. H. M.; Caramelli, D., Cronin, L. PNAS, 2023, 120 - Automated Qualitative and Quantitative Analysis of Complex Forensic Drug Samples using 1H NMR
Mehr, S. H. M.; Tang, A. W.; Laing, R. R. Magn. Reson. Chem., 2023, 61, 95–105
2022
- Digitization and validation of a chemical synthesis literature database in the ChemPU
Rohrbach, S.; Šiaučiulis, M.; Chisholm, G.; Pirvan, P.-A.; Saleeb, M.; Mehr, S. H. M.; Trushina, E.; et al. Science, 2022, 377, 172–180